Cetylpyridinium Chloride

CAS No. 123-03-5

Cetylpyridinium Chloride( Cetylpyridinium chloride | NSC 14864 )

Catalog No. M17896 CAS No. 123-03-5

Cetylpyridinium chloride is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Cetylpyridinium Chloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Cetylpyridinium chloride is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.
  • Description
    Cetylpyridinium chloride is a Germicide, Bactericide, and Disinfectant.(In Vitro):Cetylpyridinium chloride interacts with dimeric viral nucleocapsid protein (known as core protein or HBcAg) specifically. Compared with other HBV inhibitors, Cetylpyridinium chloride achieves significantly better reduction of HBV particle number in HepG2.2.15 cell line. Cetylpyridinium chloride inhibits capsid assembly and leads to reduced HBV biogenesis.Cetylpyridinium chloride is a safe antimicrobial agent with broad-spectrum activity for preventing biofilm formation and gingivitis.(In Vivo):Cetylpyridinium chloride (30 μg/kg; intramuscular injection; daily; for 3 days; male C57BL/6 mice) treatment inhibits HBV replication in mouse hydrodynamic model system.
  • In Vitro
    Cetylpyridinium chloride interacts with dimeric viral nucleocapsid protein (known as core protein or HBcAg) specifically. Compared with other HBV inhibitors, Cetylpyridinium chloride achieves significantly better reduction of HBV particle number in HepG2.2.15 cell line. Cetylpyridinium chloride inhibits capsid assembly and leads to reduced HBV biogenesis.Cetylpyridinium chloride is a safe antimicrobial agent with broad-spectrum activity for preventing biofilm formation and gingivitis.
  • In Vivo
    Cetylpyridinium chloride (30 μg/kg; intramuscular injection; daily; for 3 days; male C57BL/6 mice) treatment inhibits HBV replication in mouse hydrodynamic model system. Animal Model:Male C57BL/6 mice (6-week old) injected with the plasmid Dosage:272?μg/kg/day Administration:Intramuscular injection; daily; for 3 days Result:Suppressed serum HBV DNA levels, decreased by 60% in day2 and 45% in day3 compared to the control.
  • Synonyms
    Cetylpyridinium chloride | NSC 14864
  • Pathway
    Angiogenesis
  • Target
    JAK
  • Recptor
    Others
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    123-03-5
  • Formula Weight
    339.99
  • Molecular Formula
    C21H38N·Cl
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?Ethanol : 100 mg/mL (294.13 m)
  • SMILES
    [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1
  • Chemical Name
    Cetylpyridinium chloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pitten FA, et al. Arzneimittelforschung. 2001, 51(7), 588-595.
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